This in-vivo skin trial evaluated Oat® COM’s skin repair properties.
Oat COM Skin Trial 3
Trial Overview
KEY POINTS
- Subjects: 15 healthy adults
- Duration: 10 days
- Methodology: Two areas on the volar forearms were pre-irritated with a 0.5% Sodium Dodecyl Sulphate solution. One area was covered with a patch coated with 0.6% Oat® COM, while the other served as an uncoated control.
- Assessment: Test sites were assessed on Day 0, after 24 hours, and on Day 5, with the rate of recovery compared.
Key Findings
Combined Tewameter and Corneometer results demonstrated that Oat® COM significantly supported an increased rate of skin repair.
The data showed a statistically significant improvement in recovery compared to the control site on Day 5 for assessments of skin hydration, skin cracking, and visual erythema. The visual erythema scores were particularly impressive.
On Day 1, assessment scores indicated moderate to severe erythema with oedema (swelling). This damage was completely resolved by Day 5 in the Oat® COM-coated patches, whereas the control test site still exhibited well-defined erythema.